Peptide Library

18 peptides
3 compounds that aren't peptides also match.
CJC-1295
CJC-1295 with DAC; CJC-1295 without DAC = Modified GRF 1-29 = Mod GRF = tetrasubstituted GRF 1-29; "CJC-1293" was a shorter-acting precursor

Activates the GHRH receptor on the pituitary, stimulating growth hormone synthesis and release; with DAC the stimulus is continuous, without DAC it produces a short pulse

Growth hormone axisAwaiting review
Ipamorelin
NNC 26-0161

Triggers a pulse of growth hormone with little effect on cortisol or prolactin.

Growth hormone axisAwaiting review
Sermorelin
GRF 1-29 · GHRH-NH₂ · sermorelin acetate; brand Geref

Activates the pituitary GHRH receptor to stimulate synthesis and pulsatile release of the body's own growth hormone

Growth hormone axisAwaiting review
Tesamorelin
Egrifta · Egrifta SV · Egrifta WR

Stimulates the pituitary GHRH receptor to increase pulsatile growth hormone release, which raises IGF-1 and preferentially mobilises visceral (deep abdominal) fat

Growth hormone axisAwaiting review
GHRP-2
pralmorelin · KP-102 · GPA-748

Mimics ghrelin at pituitary and hypothalamic receptors to release a large pulse of growth hormone, and also raises cortisol, ACTH and prolactin and stimulates appetite

Growth hormone axisAwaiting review
GHRP-6
Growth hormone releasing peptide-6 · GHRP · SKF-110679

Activates the ghrelin receptor in the pituitary and hypothalamus, releasing a pulse of growth hormone; also raises appetite, cortisol and prolactin

Growth hormone axisAwaiting review
Hexarelin
Examorelin · EP 23905 · His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2

Releases a large pulse of growth hormone via the ghrelin receptor; the most potent injectable GHRP, but also raises cortisol and prolactin and desensitises with repeated use

Growth hormone axisAwaiting review
IGF-1 LR3
Long R3 IGF-1 · LR3-IGF-I · Long arginine-3 insulin-like growth factor-1

Activates the IGF-1 receptor like native IGF-1 but barely binds the IGF-binding proteins that normally buffer it, so more stays free and active for longer

Growth hormone axisAwaiting review
MGF / PEG-MGF
Mechano growth factor · IGF-1Ec / IGF-1Eb · MGF E-peptide

Proposed to activate muscle satellite (stem) cells and delay their differentiation, expanding the pool available for repair — through a receptor that has never been identified

Growth hormone axisAwaiting review
Follistatin-344
FST-344 · follistatin · FS-344; related: FST-315

Traps myostatin and activin before they can reach their receptors, removing a brake on muscle growth and altering reproductive and metabolic signalling

Growth hormone axisAwaiting review
Mod GRF 1-29
Modified GRF 1-29 · "CJC-1295 without DAC" · "CJC-1295 no DAC"

Acts on the GHRH receptor in the pituitary to trigger a pulse of growth hormone; the four substitutions slow enzymatic clearance so the pulse is larger and longer than with native GHRH

Growth hormone axisAwaiting review
GHRP-1
Growth hormone-releasing peptide-1 · GHRP1

Mimics ghrelin at the pituitary and hypothalamus to release a pulse of growth hormone, with the GHRP-6-type side effects on appetite, cortisol and prolactin

Growth hormone axisAwaiting review
Alexamorelin
Ala-hexarelin · Ala-His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2

Mimics ghrelin to release a pulse of growth hormone from the pituitary; like hexarelin it also produces small rises in prolactin, ACTH and cortisol

Growth hormone axisAwaiting review
Somatropin
Recombinant human growth hormone · rhGH · GH

Binds the GH receptor on liver, muscle, bone and fat; drives IGF-1 production and acts directly to promote growth, protein synthesis, fat breakdown and reduced insulin sensitivity

Growth hormone axisAwaiting review
IGF-1 DES(1-3)
desIGF-I · des-IGF-1 · truncated IGF-1

Activates the IGF-1 receptor like IGF-1 but binds far more weakly to IGF-binding proteins, so more of it is free and active — roughly 10 times as potent as IGF-1 in cell culture

Growth hormone axisAwaiting review
IGF-2
Insulin-like growth factor 2 · IGF-II · somatomedin A

Signals through the IGF-1 receptor and the A isoform of the insulin receptor to promote growth and survival, while a third receptor (IGF2R) mops it up; in adults it is mainly a fetal and tissue-level growth factor rather than a GH-driven…

Growth hormone axisAwaiting review
Macimorelin
Macrilen · AEZS-130 · ARD-07

Mimics ghrelin to trigger a measured pulse of growth hormone from the pituitary; a weak pulse indicates GH deficiency

Growth hormone axisAwaiting review
Vosoritide
Voxzogo · BMN 111 · CNP analogue

Activates the natriuretic peptide receptor B (NPR-B) on growth-plate cartilage cells, raising cGMP, which switches off the overactive FGFR3–MAPK signalling that stops bone growth in achondroplasia

Growth hormone axis · Clinical or research use onlyAwaiting review
Evidence gradesA Human RCTB Human, small/uncontrolledC AnimalD In vitro / theoretical— Anecdotal only

Looking for MK-677, NAD+ or rapamycin? They aren't peptides — see Not a peptide, but often discussed with them.